EFFECTS OF EARLY GEOMETRIC CONFINEMENT ON THE TRANSCRIPTOMIC PROFILE OF HUMAN CEREBRAL ORGANOIDS

Abstract Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain Christmas Stocking regions and transcriptomics of early in vivo brain development.To date, they have been used to understand the effects of genetics and soluble factors on neurodevelopment.Interestingly, one of the main advantages

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